Genetic testing and breast cancer

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Who will be offered genetic testing? How is the test done? Getting your predictive genetic test results 4.

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Women who have inherited mutations in these genes are at an increased risk of developing breast cancer and ovarian cancer compared with the general population. The BRCA gene test is offered only to people who are likely to have an inherited mutation based on personal or family history, or who have a specific type of breast cancer. The BRCA gene test isn't routinely performed on women at average risk of breast and ovarian cancers.

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Mutations in these genes have been linked to a higher risk of breast cancer and ovarian cancer. Cancer is also more likely to develop at an earlier age. A genetic counselor can help you understand if you're likely to have an inherited susceptibility to breast or ovarian cancer.

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Breast cancer is the most common type of cancer in women in British Columbia. Breast cancer can occur in men as well, but it is not as common. Tests and treatments for breast cancer vary from person to person, and are based on individual circumstances.

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The test does not guarantee who will or will not get breast cancer or ovarian cancer. While it's important for every woman to understand her individual risk, genetic testing may not be the right option for everyone. Sofia Merajver, provides individuals with an accurate assessment of their personal risk for developing breast cancer or ovarian cancer and offers a plan for follow-up and preventive care.

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Back to Health A to Z. BRCA genes are not the only cancer risk genes. Researchers recently identified more than new gene variants associated with an increased risk of breast, prostate and ovarian cancer.

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Find information and resources for current and returning patients. Learn about clinical trials at MD Anderson and search our database for open studies. The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services.

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When either of these genes is mutated, or altered, such that its protein product is not made or does not function correctly, DNA damage may not be repaired properly. As a result, cells are more likely to develop additional genetic alterations that can lead to cancer. People who have inherited mutations in BRCA1 and BRCA2 tend to develop breast and ovarian cancers at younger ages than people who do not have these mutations. Like women from the general population, those with harmful BRCA1 or BRCA2 mutations also have a high risk of developing a new primary cancer in the opposite contralateral breast in the years following a breast cancer diagnosis.

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The choice to have genetic counseling and proceed with genetic testing is one to be taken seriously and with some caution. Though it can sound simple to be tested, there are many things to consider before making this decision. Our physicians and nurses will help guide you through the entire process so you understand the pros and cons of genetic testing.

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Genetic testing gives people the chance to learn if their breast cancer or family history of breast cancer is due to an inherited gene mutation. This section provides information on genetic counseling and testing for gene mutations that increase breast cancer risk. It also has information on inherited gene mutations and other related topics, such as the benefits and risks of testing, direct-to-consumer genetic testing and testing for multiple high-risk gene mutations panel testing. In the U.


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